Lab 4x Hello Python - Calculate sum of prime numbers from 1 to N, (create boolean function?)

def setup():
    sum_prime_number(10)
   
def sum_prime_number(numbers_end):
    numbers=2
    sum=0
    n=1
    print("Prime number is ",end="")
    while(numbers<=numbers_end):
        reference=2
        prime_numbers=True
        while(reference<numbers and prime_numbers):
            if(numbers%reference==0):
                prime_numbers=False
            reference=reference+1
        if(prime_numbers):
            sum=sum+numbers
            print(numbers,"",end="")
            n=n+1
        numbers=numbers+1
    print("")
    print("Sum of prime number is ",sum)
   
setup()